For time-resolved fluorescence simulations, the reflectance and fluorescence from skin were determined by solving the transient radiative transfer equation using the modified method of characteristics. The fluorophore lifetimes were then recovered from the simulated fluorescence decays and compared with the actual lifetimes used in the simulations. Furthermore, the effect of adding Poissonian noise to the simulated decays on recovering the lifetimes was studied. Finally, the feasibility of an epidermal glucose sensor based on time-resolved fluorescence is evaluated. It was found that glucose concentrations within the skin were recovered within 13.5 % of their actual values, indicating a possibility of measuring glucose concentrations using a time-resolved fluorescence sensor.A liquid light guide designed for the UV- visible part of the spectrum (77628, from Spectra-Physics, U.S. A) carried light ... the device, the user is strongly advised to read the user manuals provide by Picoquant GmbH, for the diode PLS 370, anbsp;...
|Title||:||Transient Radiation Transport in Biological Tissues and Applications to Autofluorescence of Human Skin|
|Publisher||:||ProQuest - 2007|