This volume contain toxicological monographs prepared at the 70th meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) which met in WHO headquarters in Geneva, Switzerland, on 21-29 October 2008. These summarise data on two veterinary drug residues evaluated by the Committee, the antimicrobial agents colistin and erythromycin. For the third antimicrobial agent, tylosin, a toxicological monograph has not been prepared, as no data were submitted, and a brief review of the tocicological information available in the scientific peer-reviewed literature did not allow an evaluation of the compound.To confirm that the observed weight loss was due to dermal exposure and not due to oral ingestion, the study was repeated following the ... study, the fur of three male and three female New Zealand albino rabbits was clipped, and the skin was abraded in three rabbits. ... No skin irritation was observed following initial treatments, and there was no evidence of contact sensitization following the challengeanbsp;...
|Title||:||Toxicological Evaluation of Certain Veterinary Drug Residues in Food|
|Author||:||Joint FAO/WHO Expert Committee on Food Additives. Meeting, World Health Organization|
|Publisher||:||World Health Organization - 2009|