This dissertation characterized, within a simulated biological environment, how applied voltage alters the electrochemical impedance of commercially pure titanium (cpTi) and, in turn, alters cpTi's in-vitro interaction with pre-osteoblasts. A newly developed potential step impedance analysis (PSIA) quantified the electrochemical impedance (solution resistance (Rs), polarization resistance (Rp), interfacial capacitance (C), and the constant phase element's exponent, (Alpha)) of the electrified interface. An electrochemical cell culture chamber was developed to potentiostatically control the voltage of the cpTi cell culture substrate and to perform PSIA.The CPE exponent alpha generally increases from -1000 mV to +1000 mV in all solutions for both the 0 hr and 24 hr results. Exceptions to this trend are noted for AMEM and AMEM+FBS at -600 mV after 24 hrs of immersion. These conditionsanbsp;...
|Title||:||The In-vitro Biological and Electrochemical Interactions of Electrically Polarized Commercially Pure Titanium Used for Orthopedic and Dental Applications|
|Author||:||Mark T. Ehrensberger|
|Publisher||:||ProQuest - 2008|