In the three volumes of qScience of Synthesis: Stereoselective Synthesisq expert authors present the best and most reliable methods currently available for the preparation of chiral nonracemic compounds. These methods may be stoichiometric or catalytic, and the latter may include metal, organic, or enzyme catalysis. qStereoselective Synthesis 3q covers stereoselective pericyclic reactions, cross coupling, and C-H and C-X activation, where the emphasis is on enantioselective reactions using asymmetric catalysts. Examples from the total synthesis of various natural and unnatural targets validate the utility of the various synthetic methods. Specific topics discussed include cycloaddition, cycloisomerization and sigmatropic rearrangement reactions, allylic and -carbonyl functionalization reactions, metal-catalyzed cross-coupling reactions, desymmetrization, fluorination, polymerization and sulfide oxidation reactions. // The content of this e-book was originally published in April 2011.Stereoselective Pericyclic Reactions, Cross Coupling, and C-H and C-X Activation Erick M. Carreira, Carl P. Decicco, P. Andrew Evans, Alois ... simple diastereocontrol, which has the potential for additional problems with respect to controlling the formation of a specific diastereomer. ... practicing synthetic organic chemist.
|Title||:||Science of Synthesis: Stereoselective Synthesis Vol. 3|
|Author||:||Erick M. Carreira, Carl P. Decicco, P. Andrew Evans, Alois Fürstner, Gary A. Molander, Paul J. Reider, Ernst Schaumann, Masakatsu Shibasaki, Eric Jim Thomas, Barry M. Trost, Johannes G. de Vries|
|Publisher||:||Georg Thieme Verlag - 2014-05-14|