This book provides an up-to-date and comprehensive overview of protein phosphatase research, a rapidly evolving field with increasing importance in our understanding of the molecular basis of cell biology and of pathological processes. The book covers dephosphorylation processes involving serine/threonine, as well as tyrosine and histidine residues, and aims to be a useful resource for both the advanced reader as well as the newcomer to the field. It is also valuable for those working in the pharmaceutical and Biotech industries.Marc C. Mumby Abstract Protein phosphatase 2A (PP2A) is a ubiquitously expressed member of the PPP gene family. ... 3.1 Introduction The ability to switch proteins between two functional states by reversible phosphorylation is a fundamental process in cellular signal transduction. ... Topics in Current Genetics , Vol.
|Author||:||Joaquín Arino, Denis Alexander|
|Publisher||:||Springer Science & Business Media - 2004-02-20|