Phospholipid-Binding Antibodies

Phospholipid-Binding Antibodies

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Historically, phospholipid binding antibodies were important in the study of syphilis. During the 1980s there was a resurgence of new interest in these antibodies due to reported associations with recurrent thrombosis, fetal loss, and other clinical disorders. Because of the variety of reported clinical associations and their occurrence in systemic autoimmune disorders, these antibodies have become important in many medical fields, such as clinical immunology, rheumatology, hematology, and obstetrics and gynecology. Phospholipid-Binding Antibodies provides in-depth reviews by specialists in these clinical areas and covers topics including the biochemistry of phospholipids, their role in coagulation, phospholipid immunology, and lupus anticoagulant and antiphospholipid antibodies by solid phase immunoassays. Other topics include thrombosis and fetal loss, as well as the role of phospholipid binding antibodies in these disorders. Antiphospholipid Syndrome and its reported clinical associations is also discussed.Before considering these phase diagrams, we should re-examine Figure 7, which illustrates the phase behavior of a one-component lipid system in excess water as a function of temperature. Between 25 and 41AdC, the lipid bilayer is in the gelanbsp;...

Title:Phospholipid-Binding Antibodies
Author:E. Nigel Harris, Thomas Exner, Graham R. V. Hughes, Ronald A. Asherson
Publisher:CRC Press - 1991-01-29


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