The dynamics of nuclear structures described in this book furnish the basis for a comprehensive understanding of how the higher-order organization and function of the nucleus is established and how it correlates with the expression of a variety of vital activities such as cell proliferation and differentiation. The resulting volume creates an invaluable source of reference for researchers in the field.For example, lamin B fused with green fluorescence protein (LBR-GFP) can be visualized throughout mitosis in living cells ... a DNA-specific fluorescent dye, a comprehensive picture of envelope dynamics can be developed (Haraguchi et al. ... In late prophase, the nuclear envelope becomes deformed and invaginates into the nucleus (4-8 min in Fig. ... Observation of fluorescently labeled nuclear proteins shows that the nuclear envelope is still intact when the mitotic spindle first formsanbsp;...
|Author||:||K. Nagata, K. Takeyasu|
|Publisher||:||Springer Science & Business Media - 2007-12-03|