Macrocyclic lactones are chemical compounds that represent the main treatment for parasitic diseases of animals, not only for helminth infections, but also a number of major ectoparasitic infestations.There has been no comprehensive book on this subject for more than a decade and this book fills this gap and provides detailed coverage of the basic science of these drugs and their mode of action, as well as their clinical use in farm and companion animals and in humans.Diagram of the two-microelectrode current clamp recording technique that we have used to examine electrophysiological effects of focal application of glutamate and ivermectin to the pharyngeal muscle of Ascaris suum. One micropipette (labelled V) is placed in the pharyngeal muscle to record the membrane potential, and a second micropipette (I) is also placed in the muscle to inject hyperpolarizinganbsp;...
|Title||:||Macrocyclic Lactones in Antiparasitic Therapy|
|Author||:||Jozef Vercruysse, Robert S. Rew|
|Publisher||:||CABI - 2002|