This book examines the genetic circuitry of the well-known qfruit fly, q tackling questions of cell assemblage and pattern formation, of the hows and the whys behind the development of the fly. After an initial examination of the proximity versus pedigree imperatives, the volume delves into bristle pattern formation and disc development, with entire chapters devoted to the leg, wing, and eye. Extensive appendices include a glossary of protein domains, catalogs of well-studied genes, and an outline of signaling pathways. More than 30 wiring diagrams among over 60 detailed schematics clarify the text.We know only part of the story: rough is kept off in R1/6 by BarH1, and svp is kept off in R7p by lozenge. ... The links among these transcription factors (excluding autoregulatory loops) are presented as a wiring diagram in Figure 7.9b, and their anbsp;...
|Author||:||Lewis I. Held, Jr., Lewis I. Held Jr, Jonathan B. L. Bard|
|Publisher||:||Cambridge University Press - 2005-08-22|