Evidence-Based Diagnosis explains diagnostic, screening, and prognostic tests in clinical medicine. The authors' approach is based on many years of experience teaching physicians in a clinical research training program. Although needing only a minimum of mathematics, the quantitative discussions in this book are deeper and more rigorous than in most introductory texts. The book includes numerous worked examples and 60 problems (with answers) based on real clinical situations and journal articles. This book is a great choice for anyone looking to select, develop, or apply medical tests. Topics covered include: the diagnostic process; test reliability and accuracy; testing and treatment thresholds; critical appraisal of studies of diagnostic, screening and prognostic tests; test independence and methods of combining tests; quantifying treatment benefits using randomized trials and observational studies; Bayesian interpretation of P values and confidence intervals; challenges for evidence-based diagnosis; likelihood ratios and ROC curves.thing is to realize that the decision to pursue a more specific diagnosis should be just that a a decision. ... antibiotics; and b) Prescribing prophylactic antibiotics to a patient with a history of UTI but without vesicoureteral reflux. ... (71.7% a 50%)/ (100% a 50%) I 21.7%/50% I 0.43 If. The disagreements are unbalanced: the diagnosis based on ICD-9 codes appears to have been looser than the consensus.
|Author||:||Thomas B. Newman, Michael A. Kohn|
|Publisher||:||Cambridge University Press - 2009-02-16|