A look at the recent oncology literature or a search of the common databases reveals a steadily increasing number of nomograms and other prognostic models. These models may predict the risk of relapse, lymphatic spread of a given malignancy, toxicity, survival, etc. Pathology information, gene signatures, and clinical data may all be used to compute the models. This trend reflects increasingly individualized treatment concepts, the need for approaches that achieve a favorable balance between effectiveness and side-effects, and the goal of optimal resource utilization reflecting prognostic knowledge. In order to avoid misuse, it is important to understand the limits and caveats of prognostic and predictive models. This book provides a comprehensive overview of such decision tools for radiation oncology, stratified by disease site, which will enable readers to make informed choices in daily clinical practice and to critically follow the future development of new tools in the field.2 Breast Cancer Staging in situ, early breast cancer, locally advanced breast cancer, and metastatic breast cancer. Figure 1 illustrates the current (7th edition) staging manual of the AJCC for breast cancer, which will be used in furtheranbsp;...
|Title||:||Decision Tools for Radiation Oncology|
|Author||:||Carsten Nieder, Laurie E. Gaspar|
|Publisher||:||Springer Science & Business Media - 2014-03-13|