Current Topics in Cellular Regulation: Volume 32 is a collection of papers that discusses the role of GTP-binding proteins in signal transduction, the activation of cholera toxin by ADP-ribosylation factors, and the signal transduction by the colony-stimulating factor-1 receptor. Other papers explain the secretory granule, the mechanism of stimulus-secretion coupling, calcium pumps in the plasma and intracellular membranes, as well as the protein phosphorylation in translational control. One paper proposes a linkage between the multimeric structures and cytoskeletal elements to bridge the signal transducing systems and the cytoskeletal network. Another paper describes the signaling mechanisms utilized by CSF-1R, the similarities, and differences when compared to other receptor tyrosine kinases (RTKs). The paper explains in detail the mechanism of ligand-induced kinase activation, and also the possible biological role of certain intracellular substrates. Another paper examines the role played by protein phosphorylation in the control of translation, or when possible, any additional regulatory mechanisms operating in other eukaryotic species. Biochemists, micro-biologists, bio-physicists, cellular researchers, and researchers involved in the study of cellular biology will find the collection very useful.The current model of G-protein structure and function discussed previously does not provide insights into this question. ... nucleotides) displayed functional target sizes of 1000 to 1500 kDa for the stimulatory processes involving glucagon andanbsp;...
|Title||:||Current Topics in Cellular Regulation|
|Author||:||Earl R. Stadtman, P. Boon Chock, Alexander Levitzki|
|Publisher||:||Elsevier - 2014-06-28|