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This volume is THE definitive, completely up-to-date, reference work for ALL researchers and clinicians working in autoimmunity. Up-to-Date: This is a timely critical review of more than 100 autoantibodies by leading experts in their respective fields, and includes many recent references. International Experts: The 120 Chapters have been written by the top international cadre of authors who have provided structured, expert contributions. Comprehensive: A total comprehensive perspective on the processes which induce, inhibit or otherwise affect autoantibodies in humans. Useful to Researchers and Clinicians: Chapters generally include methods of detection, pathogenic role, factors in pathogenicity and genetics as well as clinical utility with disease associations and frequencies.Exploded diagrammatic structure of the core particle of ... This discovery was soon followed by detection of antibodies to the H2A-H2B complex in patients with procainamide-induced lupus (Totoritis et al., ... This structure is linked to the adjacent core particle by 20 to 60 base pairs of DNA with one molecule of histone H1, anbsp;...

Author:J.B. Peter, Yehuda Shoenfeld
Publisher:Elsevier - 1996-07-17


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