Born out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case studies. Like its precursor, this volume also contains a general section discussing universally applicable strategies for analog discovery and development. Spanning a wide range of therapeutic fields and chemical classes, the two volumes together constitute the first systematic approach to drug analog development. Of interest to virtually every researcher working in drug discovery and pharmaceutical chemistry.John Deere Co., 383 U.S. 1, (1966) (US Supreme Court). ... Instead, the structurally more distant drug omeprazole that contains a methoxy substituent was the proper comparison drug; see www.cafc. uscourts.gov/opinions/07-1397. pdf. ... 5 US Manual of Patent Examining Practice (2008): http://www.uspto.gov/ web/offices/anbsp;...
|Title||:||Analogue-based Drug Discovery II|
|Author||:||Janos Fischer, C. Robin Ganellin|
|Publisher||:||John Wiley & Sons - 2010-08-24|