The complexity of biological systems and the need to design and develop biomedical therapies poses major challenges to professionals in the biomedical disciplines. An Introduction to Biomaterials emphasizes applications of biomaterials for patient care. Containing chapters prepared by leading authorities on key biomaterial types, this book underscores the process of biomaterial design, development directed toward clinical application, and testing that leads to therapies for clinical targets. The authors provide a lucid perspective on the standards available and the logic behind the standards in which biomaterials address clinical needs. This volume includes chapters on consensus standards and regulatory approaches to testing paradigms, followed by an analysis of specific classes of biomaterials. The book closes with sections on clinical topics that integrate materials sciences and patient applications.Natural scaffolds include collagen gels or sponges as well as hyaluronic acid and its derivatives. ... Growth factors and other substances can be encapsulated within scaffolds for controlled release over defined periods of time. ... features for a scaffold suitable for cartilage tissue engineering include the ability to support chondrogenesis, biocompatibility and ease of use. ... scaffolds are being studied clinically in the repair of chondral defects (Pavesio et al., 2003; Dickinson et al., 2005).
|Title||:||An Introduction to Biomaterials|
|Author||:||Jeffrey O. Hollinger|
|Publisher||:||CRC Press - 2005-12-21|